PeptiCode™ HP-9
Naturally Advanced
Anti-aging Solution
Optimising nature for advanced peptide solutions
PeptiCode™ HP-9 is the first European biotech Hexapeptide-9, developed through the PeptiCode™ biotechnology platform based in France. This platform specialises in the optimisation of various microorganisms – such as bacteria, yeast, and microalgae – through strain engineering and fermentation technologies, in order to unlock access to sustainable, naturally-derived, bio-identical sequence peptides.
PeptiCode™ HP-9 is created via precision fermentation, harnessing the power of an optimised microorganism to synthetise a pure, 100% natural origin and bio-identical hexapeptide-9. SEQENS’ process ensures high performance and optimal peptide stability without using TFA (trifluoroacetic acid) or PFAS (per- and polyfluoroalkyl substances) during production and complies with the principles of Green Engineering.
PeptiCode™ HP-9: For your next-generation anti-aging formulations
Collagen Booster &
Drop in Replacement
PeptiCode™ HP-9 is an hexapeptide-9 with the sequence Glycyl-L-prolyl-Lglutaminylglycyl-L-prolyl-L-glutamine (or Gly-Pro-Gln-Gly-Pro-Gln or GPQGPQ).
It is a peptide present inside the amino acid sequence of type 4 and 17 collagen.
As we age,the synthesis of collagen diminishes, especially type 1 and 4 collagen, resulting in weakened skin structure and wrinkle formation. PeptiCode™ HP-9 is a signal peptide that stimulates collagen synthesis.
- 1st SEQENS hexapeptide-9 produced by Green Technology: biotechnology
- Respecting the principles of Green Engineering
- No TFA & no PFAS used in production process
- 100% natural origin for the product and the pure peptide
- ISO16128, NOC =100%
- Quality analysis and high purity criteria (> 95%, without other peptides)
- Safe and controlled environment for workers
- Drop-in replacement for the synthetic efficacy equivalency
- INCI: AQUA, BUTYLENE GLYCOL, HEXAPEPTIDE-9
- Recommended use level: 1-3%
Synthesised by Classical Solution Peptide Synthesis (CSPS)
Solid phase Peptide Synthesis revolutionized peptide production
Synthetic peptide GHK as a signal peptide enhancing collagen production and acting as a carier peptide when complexed with CU(II)
of Pentapeptide-4 ( KTTKS) and substance P antagonists into comestcs formulations
Plethora of peptides of cosmeceutical interest developed through synthetic and biotech processes.
Thanks to their versatility and synthetic production, peptides are now widely used in anti-aging products. Additionally, conscious consumers seek out more and more ingredients that are both sustainable and effective, fuelling the movement toward more scientific beauty solutions, innovative ingredients, and biotechnology.Peptides have become essential in cosmetics since their introduction in 1973 with the collagen-boosting peptide GHK (Gly-L-His-L-Lys). In 2025, anti-aging represented 48% of the peptide synthesis market application share*.
Peptides have become essential in cosmetics since their introduction in 1973 with the collagen-boosting peptide GHK (Gly-L-His-L-Lys). In 2025, anti-aging represented 48% of the peptide synthesis market application share
