Technical characteristics

Vitamin E TPGS

Certification: GMP

Vitamin E TPGS is a surfactant which can be used as emulsifier, drug solubilizer, absorption enhancer, and as a vehicle for lipid-based, drug delivery formulations.

PROPERTIES OF VITAMIN E TPGS

  • Improving Drug Bioavailability Surfactant properties enhance solubilization of poorly water soluble drugs

-Stabilization of amorphous drug
-Enhances drug permeability by P-glycoprotein efflux inhibition.
-Emulsion vehicle

  • Functional Ingredient in self-emulsifying formulations
  • Thermal binder in melt granulation/extrusion processing
  • Reducing drug sensitivity on skin or tissues
  • Carrier for wound care and treatment
  • Water soluble source of Vitamin E

APPLICATION FIELD OF VITAMIN E TPGS

Due to its properties, Vitamin E TPGS is used for various applications:

  • Pharmaceutical
  • Nutraceuticals
  • Food & Beverage
  • Cosmetic & Personal Care
  • Animal Nutrition

Our location

Address Raiffeisenstraße 4
77933 Lahr
Business Line Custom Manufacturing, APIs & Intermediates
Phone 49 7821 585 0
Market Pharmaceutical
Email info-lahr@seqens.com
More information

Surface: 48, 000 m²

Lab surface: 700 m²

Capabilities:

  • Total reactor capacity: 92 m³
  • Reaction vessels: 1 to 6 300 L; temperature  -80°C to +250 °C
  • Multi-purpose state of the art cGMP facilty: 4 independent, vertical integrated production trains 800 L train, 2 x 3 000 L trains plus 1 x 3 000 L low temperature hydrogenation reactor and 6 000 L train
  • Classic two-floor layout Facility: 20 vessels with capacity between 800 and 6 000 L (glaslined and SS)
  • Autoclaves (operational range up to 100 bar)
  • Kilo-Lab: 3 reactors: 25 / 100 / 250 L

Flagship technologies:

  • Hydrogenation
  • Reductive amination
  • Organometallic reactions
  • Protected AADs (Aminoacid derivatives)
  • Carbonylation & Hydroformylation
  • Pressure aminolysis, other reactions under pressure
  • Cryogenic chemistry
  • Enantiopure synthesis
  • Cyanation high volumes (NaCN) C-C coupling
  • Reductions
  • Halogenation

Last inspections:

  • FDA 2018
  • German Pharma Authority 2018

Certifications:

  • GMP
  • ISO 9001
  • ISO 50001

Number of scientists: 25