Vitamin E TPGS

Technical characteristics

Vitamin E TPGS

CAS : 9002-96-4

Chemical Name: D-α tocopheryl polyethylene glycol 1000 succinate

US type IV

Certification GMP

VITAMIN E TPGS comes from the esterification of Vitamin E succinate with PEG 1000. It’s a multirole excipient for drug delivery formulations.

Improving Drug Bioavailability Surfactant properties enhance solubilization of poorly water soluble drugs

-Stabilization of amorphous drug
-Enhances drug permeability by P-glycoprotein efflux inhibition
-Emulsion vehicle

Due to its properties, Vitamin E TPGS is used for various applications:

Manufacturing site

Address Uetikon, Raiffeisenstraße 4
77933 Lahr

Business Line Custom Manufacturing, APIs & Intermediates

Phone 49 7821 585 0

Market Pharmaceutical

Email info-lahr@seqens.com

More information

Surface: 48, 000 m²

Lab surface: 700 m²

Capabilities:

Total reactor capacity: 92 m³
Reaction vessels: 1 to 6 300 L; temperature -80°C to +250 °C
Multi-purpose state of the art cGMP facilty: 4 independent, vertical integrated production trains 800 L train, 2 x 3 000 L trains plus 1 x 3 000 L low temperature hydrogenation reactor and 6 000 L train
Classic two-floor layout Facility: 20 vessels with capacity between 800 and 6 000 L (glaslined and SS)
Autoclaves (operational range up to 100 bar)
Kilo-Lab: 3 reactors: 25 / 100 / 250 L

Flagship technologies:

Last inspections:

Certifications:

Number of scientists: 25

EcoVadis CSR Rating: Gold Certification