Technical characteristics

Di-n-Butyl Ether

CAS N°: 142-96-1

Empirical Formula: C8H18O

Synonyms: Butyl ether

Physical State: Colourless liquid

Odour: Ether

Boiling Point: 142.4°C

WHAT IS DI-N-BUTYL ETHER?

Di-n-Butyl ether is a speciality solvent that is finding increasing use as a replacement for THF in Grignard, Wittig and other organo-metallic reactions and is used in the production of CD-R.

Applications

Di-n-Butyl Ether is a powerful and cost effective solvent for Grignard reactions, particularly those with β-hydrogens increasing the yield of addition products.

It is a good solvent for oils and fats and some natural and synthetic resins. Its properties make it robust for use with either organic acids or alkalis. It is used in the manufacturing process of a range of pharmaceutical API’s such Procarbazine and Cefaclor. It is also used in the manufacture of agrochemicals such as Cyhexatin. CD-R manufacture uses Di-n-butyl Ether as the principle solvent for the application of the coating. It has over 23,000 references in SciFinder and is the key solvent in over 300 patents. It is used widely in Alkyl Lithium, Wittig and other organo-metallic reactions

Di-n-butyl ether is an excellent choice of solvent both commercially and technically for a wide range of synthetic reactions and processes where its low water and peroxide content and high boiling point allows for higher process temperatures. Its flash point is higher than other conventional solvents adding to its safety aspects, and it is a much easier solvent to recover after use than THF, making the process more economic.

Our locations

Address Road 11 CF Fertilizer Process Park
TS23 1PY Billingham
Business Line Solvent Recovery
Phone +44 1642 248555
Market Specialty Ingredients
Email info.CS@seqens.com
More information

Surface: 42, 000 m²

Capabilities:

  • 3 reaction vessels (316 L and Duplex 2205) of 25-35 m³ capacity with associated distillation columns of 6-30 plates
  • Glass lined reaction vessel (14 m³)

Flagship technologies:

 Primary Reactions

  • Esterification
  • Etherification
  • Epoxidation
  • Methylation/Methyl chloride capping
  • Quaternisation
  • Transeterification.

Secondary reactions

  • Acetal formation
  • Acetylation
  • Aldol condensation,
  • Alkylation
  • Diels-Alder
  • Hydrolysis
  • Isomerisation
  • Oxidation
  • Polymerisation

Solvent Recovery

  • Alcohols,
  • Amines
  • Aromatic solvents
  • Esters
  • Glycols
  • Ketones
  • Organic acids

Certifications:

Address All Saints Refinery, Cargo Fleet Road, Cleveland,
TS3 6AF Middlesbrough
Business Line Solvent Recovery
Phone +44 1642 248555
Market Specialty Ingredients
Email info.CS@seqens.com
More information

Surface: 68, 000 m²

Capabilities:

  • 48 plate distillation column
  • 18 plate distillation column
  • 4 reaction vessels (316 L and Duplex 2205) of 25-30m³ capacity with distillation columns attached (6-30 plates)

Flagship technologies:

 Primary Reactions

  • Esterification
  • Etherification
  • Epoxidation
  • Methylation/Methyl chloride capping
  • Quaternisation
  • Transesterification.

Secondary reactions

  • Acetal formation
  • Acetylation
  • Aldol condensation,
  • Alkylation
  • Diels-Alder
  • Hydrolysis
  • Isomerisation
  • Oxidation
  • Polymerisation

Solvent Recovery

  • Alcohols,
  • Amines
  • Aromatic solvents
  • Esters
  • Glycols
  • Ketones
  • Organic acids

Certifications: