Di-n-Butyl Ether
Di-n-Butyl ether is one of the multitudes of useful, high-quality chemical products available from SEQENS Custom Specialties.
Technical characteristics
Di-n-Butyl EtherCAS N°: 142-96-1
Empirical Formula: C8H18O
Synonyms: Butyl ether
Physical State: Colourless liquid
Odour: Ether
Boiling Point: 142.4°C

WHAT IS DI-N-BUTYL ETHER?
Di-n-Butyl ether is a speciality solvent that is finding increasing use as a replacement for THF in Grignard, Wittig and other organo-metallic reactions and is used in the production of CD-R.
Applications
Di-n-Butyl Ether is a powerful and cost effective solvent for Grignard reactions, particularly those with β-hydrogens increasing the yield of addition products.
It is a good solvent for oils and fats and some natural and synthetic resins. Its properties make it robust for use with either organic acids or alkalis. It is used in the manufacturing process of a range of pharmaceutical API’s such Procarbazine and Cefaclor. It is also used in the manufacture of agrochemicals such as Cyhexatin. CD-R manufacture uses Di-n-butyl Ether as the principle solvent for the application of the coating. It has over 23,000 references in SciFinder and is the key solvent in over 300 patents. It is used widely in Alkyl Lithium, Wittig and other organo-metallic reactions
Di-n-butyl ether is an excellent choice of solvent both commercially and technically for a wide range of synthetic reactions and processes where its low water and peroxide content and high boiling point allows for higher process temperatures. Its flash point is higher than other conventional solvents adding to its safety aspects, and it is a much easier solvent to recover after use than THF, making the process more economic.
This product is also part of the Modens range, polar modifiers for high performance styrenic block copolymers, offered by Seqens Advanced Specialties.
Our locations
Custom Specialties Billingham
United KingdomTS23 1PY Billingham
Surface: 42, 000 m²
Capabilities:
- 4 reaction vessels (316 L and Duplex 2205) of 25-35 m³ capacity with associated distillation columns of 6-30 plates
- Glass lined reaction vessel (14 m³)
Flagship technologies:
Primary Reactions
- Esterification
- Etherification
- Epoxidation
- Methylation/Methyl chloride capping
- Quaternisation
- Transeterification.
Secondary reactions
- Acetal formation
- Acetylation
- Aldol condensation,
- Alkylation
- Diels-Alder
- Hydrolysis
- Isomerisation
- Oxidation
- Polymerisation
Solvent Recovery
- Alcohols,
- Amines
- Aromatic solvents
- Esters
- Glycols
- Ketones
- Organic acids
Certifications:
- ISO 9001
- ISO 14001
- EcoVadis CSR Rating: Gold Certification
Custom Specialties Middlesbrough
United KingdomTS3 6AF Middlesbrough
Surface: 68, 000 m²
Capabilities:
- 48 plate distillation column
- 18 plate distillation column
- 4 reaction vessels (316 L and Duplex 2205) of 25-30m³ capacity with distillation columns attached (6-30 plates)
Flagship technologies:
Primary Reactions
- Esterification
- Etherification
- Epoxidation
- Methylation/Methyl chloride capping
- Quaternisation
- Transesterification.
Secondary reactions
- Acetal formation
- Acetylation
- Aldol condensation,
- Alkylation
- Diels-Alder
- Hydrolysis
- Isomerisation
- Oxidation
- Polymerisation
Solvent Recovery
- Alcohols,
- Amines
- Aromatic solvents
- Esters
- Glycols
- Ketones
- Organic acids
Certifications:
- ISO 9001
- ISO 14001
- EcoVadis CSR Rating: Gold Certification