Technical characteristics

Acetylsalicylic Acid

CAS N°: 50-78-2

Solid state available : crystal, powder, granules

100% API

Our grades

Crystal grades

  • Nine grades of ASA crystal are manufactured within EDS production sites from coarse to fine particles.
  • These crystal grades can be blended with others ingredients, excipients and are suitable for various finished dosage forms such as sachets, tablets, capsules, chewable tablets…

Milled

  • 2 grades of ASA powder are available from our sites.
  • Their excellent dissolution properties make them particularly suitable for effervescent tablets and suppositories applications.

Granular 

  • Only dry granulation is suitable for aspirin as it is sensitive to humidity. 2 types of granular grades are manufactured within EDS :  100% ASA  and 90% ASA granulates.
  • Both granulates type of products are compliant with US and EU pharmacopeias and exhibit excellent flow properties.
  • 100% ASA granulates are particularly recommended for formulated tablets, high speed tableting machines and exhibit excellent dissolution.
  • The four grades containing 90% aspirin are directly compressible as is. They are suitable for slow or fast release and can be compressed with excipients and APIs.

Main applications

  • Anti-inflammatory
  • Mild to intense pain treatment
  • Fever treatment
  • Cardiovascular diseases prevention (myocardial infection, strokes, arterial thromboembolic events, etc.)

Under study applications

Cancers prevention

  • Effects of large magnitude on colorectal, esophageal and gastric cancers
  • Effects of smaller magnitude on breast, prostate and lung cancers

Anti-Phospholipid Syndrome (Hughes Syndrome)

Ref: Steven P. Dehmer and others, ‘Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force’, Annals of Internal Medicine, 164.12 (2016), 777 <

Our locations

Address Rue Prosper Monnet
69190 Saint-Fons
Business Line Acetylsalicylic Acid
Phone +33 4 26 99 18 00
Market Pharmaceutical
Email info.EDS@seqens.com
More information

Capabilities: 6 KT of Acetylsalicylic Acid

Certifications:

  • cGMP
  • ISO 9001
  • ISO 14001
  • OHSAS 18001
Address 321 Bangpoo, IND Estate
10280 Samut Prakan
Business Line Acetylsalicylic Acid
Phone 66 2 324 0024
Market Pharmaceutical
Email info.EDS@seqens.com
More information

Surface: 24, 000 m²

 

Lab surface: 100 m²

Capabilities: 3.5 KT ASA

Flagship technologies: 

  • Continuous Acetylsalicylic
  • Acid Production Recycled
  • Salicyclic Acid (Industrial-grade)

Last inspections: 

  • USFDA, March 2018
  • TFDA, May 2018

Certifications: 

  • ISO 9001 
  • ISO 14001
  • OHSAS 18001

Number of scientists: 11