Acetylsalicylic Acid

Our grades

Crystal grades

• Nine grades of ASA crystal are manufactured within CHC production sites from coarse to fine particles.
• These crystal grades can be blended with others ingredients, excipients and are suitable for various finished dosage forms such as sachets, tablets, capsules, chewable tablets…

Milled

• 2 grades of ASA powder are available from our sites.
• Their excellent dissolution properties make them particularly suitable for effervescent tablets and suppositories applications.

Granular 

• Only dry granulation is suitable for aspirin as it is sensitive to humidity. 2 types of granular grades are manufactured within CHC : 100% ASA and 90% ASA granulates.
• Both granulates type of products are compliant with US and EU pharmacopeias and exhibit excellent flow properties.
• 100% ASA granulates are particularly recommended for formulated tablets, high speed tableting machines and exhibit excellent dissolution.
• The four grades containing 90% aspirin are directly compressible as is. They are suitable for slow or fast release and can be compressed with excipients and APIs.

Main applications

• Anti-inflammatory
• Analgesic
• Antipyretic
• Animal health
• Cardiovascular diseases prevention (myocardial infection, strokes, arterial thromboembolic events, etc.)

Under study applications

Oncology

• Effects of large magnitude on colorectal, esophageal and gastric cancers

• Effects of smaller magnitude on breast, prostate and lung cancers

Anti-Phospholipid Syndrome (Hughes Syndrome)

Ref: Steven P. Dehmer and others, ‘Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force’, Annals of Internal Medicine, 164.12 (2016), 777 <