(+)-2,3-Pinanediol

Surface: 40, 000 m²

Lab surface: 2, 000 m²

Capabilities:

• 6 kilo-labs
• 2 cGMP pilot plants with 11 multipurpose reactors from 100 L to 2, 800 L (total capacity of 12 m³)
• Temperature range: -15/+150°C  (hastelloy reactor: -80/+200°C)
• 3 finishing rooms (agitated filter dryers, filters, dryers, milling and sieving equipments)

Flagship technologies:

• Crystallization expertise and technologiesd(salt, co-crystal and polymorph screenings, process development)
• Process Safety expertise and tecnologies
• Flow chemistry for fine chemicals
• Potent API process development
• Genotoxic Impurities
• Issue Management
• Generic A.P.I Solid state expertise

Last inspection: ANSM  October 2018

Certification: GMP

Number of scientists: 110

Other: Ecosystem Pharma with integrated services

Capabilities: 

• 65 m³ of reactors
• 100 L – 2 500 L vessels

EcoVadis CSR Rating: Gold Certification

Last inspections:

• ANSM 2019
• ANVISA (Brasil) 2018
• FDA 2016

Capabilities: 

• 70 m³ of GMP reactors
• 100 L – 8 000 L vessels

Flagship technologies: 

• Optical resolution
• Enzymatic hydrolysis
• Enantioselective reduction
• Low-temperature reactions (-80 °C)
• Specific reduction
• Hydrogenation (40 bar)
• Organomagnesium compounds
• Thin-layer distillation

EcoVadis CSR Rating: Gold Certification 2019

Last inspections:

• FDA 2018
• ANSM 2019

Flagship technologies: Distillation

EcoVadis CSR Rating: Gold Certification

Capabilities: 

• 100 m³ of GMP reactors
• 50 L – 10 000 L vessels

Flagship technologies: 

• Organometallic chemistry
• Large-scale hydrogenation
• Diborane chemistry
• Ethylene oxide reactions
• Biocatalysis platform
• Polymer production (PLGA)
• Enzymatic synthesis Skraup reactions

EcoVadis CSR Rating: Silver certification

Last inspections:

• FDA 2018
• ANSM 2021

Surface: 11, 678 m²

Lab surface: 695 m²

Capabilities: 

• 4 separate modules
• 72 m³ reactor capacity-
• 250 L – 6300 L vessels

Flagship technologies:

• Biphosphonate chemistry
• Hydrogenation (20 bar)
• Chlorination
• Cyanation (NaCN) in separate installations
• Reduction with complex hydrids
• Biocatalysis
• Manufacturing of parenteral/injectable APIs
• Separate production modules and final processing facilities

Last inspections:

• FDA 2019
• PMDA 2018
• FIMEA 2018

Number of scientists: 16

EcoVadis CSR Rating: Silver Certification