A leader in Pharmaceutical solutions

Mastering a wide range of technologies, Seqens provide their clients with custom manufacturing services as well as a broad portfolio of Active Pharmaceutical Ingredients (APIs) & intermediates. Seqens offer technical excellence, continuous improvement plans and innovative tailor made solutions from a network of 4 R&D centers serving the Pharmaceutical market, 4 pilot units and 12 cGMP sites, including 6 cGMP multi-purposes manufacturing sites.

Seqens ensure seamless in-house process development, scale-up and manufacturing from early clinical phases to the commercial stage, in order to accompany fast track market access for their clients. Throughout its diversified network, Seqens provide their customers with secured supply chain, based on vertical integration from raw materials to APIs manufacturing.

  • Seqens is a leading provider of organic chemistry solutions for the pharmaceutical market
  • We support the pharmaceutical companies, from biotechs to large pharmas, from the pre-clinical to the commercial phases
  • We have 250 chemical engineers and scientists and 120 PhDs
  • We leverage our continuum of technologies, from R&D to mass API production
  • Additionally we have a portfolio of 70 on-the-shelf APIs that we provide to our clients, with the required regulatory support for marketing in more than 100 countries
  • We run integrated facilities that manufacture a number of input products for the life science industry

Our locations

Address Seqens, Baohua City Jingdian Building, Room 806 No. 518, Anyuan Road, Putuo District
200060 Shanghai
Phone BU Cosmetics: +86 (0)21 8031 6534
BU AS / Electronic chemicals: +86 (0)21 8031 6535
BU AS / Lubricant Additives: +86 (0)21 8031 6536
BU EDS: +86 (0)21 8031 6537
Email advanced-asia@seqens.com
Address Seqens, 21 Chemin de la Sauvegarde
69134 Ecully
Phone +33 4 26 99 18 00
Email Accueil@seqens.com
More information
  • Seqens Group headquarter
  • Essential Drug Substances headquarter
  • Solvent & Phenol Specialties headquarter
  • Acid & Derivatives headquarter
Address PCI Synthesis, 88 Jackson Road, Building 649
MA 01434 Devens
Phone (978) 772 2111
Market Pharmaceutical
Email Accueil@seqens.com
More information

Lab surface: 1, 000 m²

Capabilities:

  • Controlled substances (Schedule II-V)
  • 5 Kilo-Labs

Number of scientists: 30

Address PCAS, ZI de Limay 2, 8 Rue de Rouen
78440 Porcheville
Phone +33 1 34 79 57 00
Market Pharmaceutical, Specialty Ingredients & Cosmetics
Email ContactSeqensPCV@seqens.com
More information

Surface: 40, 000 m²

Lab surface: 2, 000 m²

Capabilities:

  • 4 kilo-labs
  • 2 cGMP pilot plants with 11 multipurpose reactors from 100 L to 2, 800 L (total capacity of 12 m³)
  • Temperature range: -15/+150°C  (hastelloy reactor: -80/+200°C)
  • 3 finishing rooms (agitated filter dryers, filters, dryers, milling and sieving equipments)

Flagship technologies:

  • Crystallization expertise and technologiesd(salt, co-crystal and polymorph screenings, process development)
  • Process Safety expertise and tecnologies
  • Flow chemistry for fine chemicals
  • Potent API process development
  • Genotoxic Impurities
  • Issue Management
  • Generic A.P.I Solid state expertise

Last inspection: ANSM  October 2018

Certification: GMP

Number of scientists: 110

Other: Ecosystem Pharma with integrated services

Address PCAS, 70 Allée Graham Bell
30000 Nîmes
Phone +33 4 66 70 64 64
Market Pharmaceutical, Specialty Ingredients & Cosmetics
Email seqensrdnimesinfo@seqens.com
More information

Surface: 1, 000 m²

Lab surface: 500 m²

Capacities:

  • 1 kilo-lab in fermentation (80 L total capacity)
  • Robotic platform for highthroughput screening (HTS)
  • Analytical platform for chromatography (GC, GC-MS, U-HPLC)

Flagship technologies: 

  • Protein engineering
  • Microbiology aerobic & anaerobic
  • Syngas fermentation
  • Enzymes & strains fermentation
  • Biochemistry
  • Biocatalysis
  • Design of experiments (DoE)
  • Data mining

Number of scientists: 19

EcoVadis CSR Rating: Silver Certification

 

Address PCAS, Expansia, Route d'Avignon
30390 Aramon
Business Line Contract Manufacturing
Phone +33 4 66 57 01 01
Market Pharmaceutical
Email info.cdmo@seqens.com
More information

Capabilities: 

  • 100 m³ of GMP reactors
  • 50 L – 10 000 L vessels

Flagship technologies: 

  • Organometallic chemistry
  • Large-scale hydrogenation
  • Diborane chemistry
  • Ethylene oxide reactions
  • Biocatalysis platform
  • Polymer production (PLGA)
  • Enzymatic synthesis Skraup reactions

EcoVadis CSR Rating: Gold certification

Address PCAS, 15 Avenue des Frères Lumière
38300 Bourgoin-Jallieu
Business Line Contract Manufacturing & Fine Chemicals
Phone +33 4 74 93 63 33
Market Pharmaceutical
Email Accueil.bourgoin@seqens.com
More information

Flagship technologies: Distillation

EcoVadis CSR Rating: Gold Certification

Address Uetikon, Raiffeisenstraße 4
77933 Lahr
Business Line Custom Manufacturing, APIs & Intermediates
Phone 49 7821 585 0
Market Pharmaceutical
Email info-lahr@seqens.com
More information

Surface: 48, 000 m²

Lab surface: 700 m²

Capabilities:

  • Total reactor capacity: 92 m³
  • Reaction vessels: 1 to 6 300 L; temperature  -80°C to +250 °C
  • Multi-purpose state of the art cGMP facilty: 4 independent, vertical integrated production trains 800 L train, 2 x 3 000 L trains plus 1 x 3 000 L low temperature hydrogenation reactor and 6 000 L train
  • Classic two-floor layout Facility: 20 vessels with capacity between 800 and 6 000 L (glaslined and SS)
  • Autoclaves (operational range up to 100 bar)
  • Kilo-Lab: 3 reactors: 25 / 100 / 250 L

Flagship technologies:

  • Hydrogenation
  • Reductive amination
  • Organometallic reactions
  • Protected AADs (Aminoacid derivatives)
  • Carbonylation & Hydroformylation
  • Pressure aminolysis, other reactions under pressure
  • Cryogenic chemistry
  • Enantiopure synthesis
  • Cyanation high volumes (NaCN) C-C coupling
  • Reductions
  • Halogenation

Last inspections:

  • FDA 2018
  • German Pharma Authority 2018

Certifications:

  • GMP
  • ISO 9001
  • ISO 50001

Number of scientists: 25

EcoVadis CSR Rating: Gold Certification

Address PCAS, 19 Route de Meulan
78520 Limay
Business Line Contract Manufacturing & APIs
Phone +33 1 34 78 87 87
Market Pharmaceutical
Email info.cdmo@seqens.com
More information

Capabilities: 

  • 70 m³ of GMP reactors
  • 100 L – 8 000 L vessels

Flagship technologies: 

  • Optical resolution
  • Enzymatic hydrolysis
  • Enantioselective reduction
  • Low-temperature reactions (-80 °C)
  • Specific reduction
  • Hydrogenation (40 bar)
  • Organomagnesium compounds
  • Thin-layer distillation

EcoVadis CSR Rating: Gold Certification

Address PCAS, Messukentänkatu 8
20210 Turku
Business Line Contract Manufacturing & Proprietary APIs
Phone +358 2 330 5542
Market Pharmaceutical
Email info.turku@seqens.com
More information

Surface: 11, 678 m²

Lab surface: 695 m²

Capabilities: 

  • 4 separate modules
  • 72 m³ reactor capacity-
  • 250 L – 6300 L vessels

Flagship technologies:

  • Biphosphonate chemistry
  • Hydrogenation (20 bar)
  • Chlorination
  • Cyanation (NaCN) in separate installations
  • Reduction with complex hydrids
  • Biocatalysis
  • Manufacturing of parenteral/injectable APIs
  • Separate production modules and final processing facilities

Last inspections:

  • FDA 2017
  • PMDA 2018
  • FIMEA 2018

Number of scientists: 16

EcoVadis CSR Rating: Silver Certification

Address PCAS, 35 Avenue Jean Jaurès
92390 Villeneuve-la-Garenne
Business Line Contract Maufacturing
Phone +33 1 46 85 91 91
Market Pharmaceutical
Email info.cdmo@seqens.com
More information

Capabilities: 

  • 65 m³ of reactors
  • 100 L – 2 500 L vessels

EcoVadis CSR Rating: Gold Certification

Address Novacyl, 321 Bangpoo, IND Estate
10280 Samut Prakan
Business Line Acetylsalicylic Acid
Phone 66 2 324 0024
Market Pharmaceutical
Email info.EDS@seqens.com
More information

Surface: 24, 000 m²

 

Lab surface: 100 m²

Capabilities: 3.5 KT ASA

Flagship technologies: 

  • Continuous Acetylsalicylic
  • Acid Production Recycled
  • Salicyclic Acid (Industrial-grade)

Last inspections: 

  • USFDA, March 2018
  • TFDA, May 2018

Certifications: 

Number of scientists: 11

Address Novacyl, Plateforme Chimique, Rue Gaston Monmousseau, CS 50032, Lieu-dit le Roussillon
38556 Roussillon
Business Line Salicylic acid & methyl salicylate
Market Pharmaceutical Synthesis
Email info.EDS@seqens.com
More information

Capabilities:

  • 20 kt Salicylic ACid
  • 6 kt Methyl Salicilate

Last inspections:

  • ANSM, February 2018
  • FDA, June 2016
  • ISO, March 2018

Certifications:

Address Novacyl, Rue Prosper Monnet
69190 Saint-Fons
Business Line Acetylsalicylic Acid
Phone +33 4 26 99 18 00
Market Pharmaceutical
Email info.EDS@seqens.com
More information

Capabilities: 6 KT of Acetylsalicylic Acid

Certifications:

  • cGMP
  • ISO 9001
  • ISO 14001
  • OHSAS 18001

EcoVadis CSR Rating: Platinum Certification

Address Novacyl (Wuxi) Pharmaceutical Co. Ltd., 16, Guangshi Road, Meijing Village, Luoshe Town, Huishan District
214185 Wuxi
Business Line Paracetamol
Phone +86 510 8101 9200
Market Pharmaceutical
Email info.EDS@seqens.com
More information

Surface: 38, 619 m²

Lab surface: 560 m²

Capabilities:

  • 8 KT of Paracetamol
  • 4.5 KT of DC range

Flagship technologies: 

  • Acetylation reaction
  • Refining, granulation

Last inspections: 

  • ANSM, January 2018
  • NMPA ,August 2018

Certifications: 

Address Novacyl, 16, Xingang South Road, Taixing Economic Development Zone, Jiangsu Province
225404 Taizhou
Business Line Para-aminophenol (PAP)
Phone +86 523 8767 1879
Market Pharmaceutical
Email Xiaoping.Chen@seqens.com
More information

Surface: 50 000 m²

Lab surface: 750 m²

Capabilities: 35 KT PAP

Flagship technologies: Catalytical hydrogenation

Last inspection: June 2017

Certifications: 

  • ISO 9001
  • ISO 14001
  • OHSAS 18001
  • Certificate of GMP issued by Norwegian Medicines Agency for PAP workshop 2 only
Address H2B, ESTER Technopole, 6 allée Skylab
87068 Limoges
Business Line Blood plasma components
Phone +33 5 19 08 00 20
Market Healthcare
Email info.ivd@seqens.com
More information

Capabilities: 5, 050 L of reactors (100 L to 2, 000 )

Flagship technologies: Blood fractionation for In Vitro Diagnostic

Certifications:

  • ISO 9001
  • ISO 14001

Number of scientists: 2

Address Novapex, Plateforme Chimique, Rue Gaston Monmousseau, CS 50032, Lieu-dit le Roussillon
38556 Roussillon
Business Line Phénol, Alphaméthylstyrène Acétophénone, Acétone Isopropanol, Acétate d'Isopropyle, Di Isoprpyl Ether
Phone +33 4 74 11 34 37
Market Specilaty ingredients
Email Info_PerfChem@seqens.com
More information

Surface : 160 000 m²

 

Capabilities: 

  • 185 kT Phenol
  • 70 kT Isopropanol
  • 27 kT Acétate Isopropyle
  • 5 kT DIPE

 

Certifications: 

  • ISO 9001
  • ISO 14001
  • ISO 50001
  • OSHAS 18001

EcoVadis CSR Rating Platinum medal

Address PCI Synthesis, 9 Opportunity Way
MA 01950 Newburyport
Business Line Custom Early Phase Pharmaceutical
Phone (978) 462 5555
Market Pharmaceutical
Email Early Stage: derek.richards@seqens.com
Custom Manufacturing: don.laferle@seqens.com
Proprietary API: laurent.alexandre@seqens.com
Address Novacyl inc., 1 Union Street, Suite 108
NJ 08691 Robbinsville
Phone +1 609 259 0444
Market Pharmaceutical
Email Theresa.Graham@seqens.com
Address PCAS, Campus Eiffel, Bâtiment Lavoisier, 11 rue Ella Maillart
91300 Massy
Email info.cdmo@seqens.com