Pharmaceutical Solutions

• Seqens Group headquarter
• Essential Drug Substances headquarter
• Solvent & Phenol Specialties headquarter
• Acid & Derivatives headquarter

Lab surface: 1, 000 m²

Capabilities:

• Controlled substances (Schedule II-V)
• 5 Kilo-Labs

Number of scientists: 30

Surface: 40, 000 m²

Lab surface: 2, 000 m²

Capabilities:

• 4 kilo-labs
• 2 cGMP pilot plants with 11 multipurpose reactors from 100 L to 2, 800 L (total capacity of 12 m³)
• Temperature range: -15/+150°C  (hastelloy reactor: -80/+200°C)
• 3 finishing rooms (agitated filter dryers, filters, dryers, milling and sieving equipments)

Flagship technologies:

• Crystallization expertise and technologiesd(salt, co-crystal and polymorph screenings, process development)
• Process Safety expertise and tecnologies
• Flow chemistry for fine chemicals
• Potent API process development
• Genotoxic Impurities
• Issue Management
• Generic A.P.I Solid state expertise

Last inspection: ANSM  October 2018

Certification: GMP

Number of scientists: 110

Other: Ecosystem Pharma with integrated services

Surface: 1, 000 m²

Lab surface: 500 m²

Capacities:

• 1 kilo-lab in fermentation (80 L total capacity)
• Robotic platform for highthroughput screening (HTS)
• Analytical platform for chromatography (GC, GC-MS, U-HPLC)

Flagship technologies: 

• Protein engineering
• Microbiology aerobic & anaerobic
• Syngas fermentation
• Enzymes & strains fermentation
• Biochemistry
• Biocatalysis
• Design of experiments (DoE)
• Data mining

Number of scientists: 19

EcoVadis CSR Rating: Silver Certification

Capabilities: 

• 100 m³ of GMP reactors
• 50 L – 10 000 L vessels

Flagship technologies: 

• Organometallic chemistry
• Large-scale hydrogenation
• Diborane chemistry
• Ethylene oxide reactions
• Biocatalysis platform
• Polymer production (PLGA)
• Enzymatic synthesis Skraup reactions

EcoVadis CSR Rating: Gold certification

Flagship technologies: Distillation

EcoVadis CSR Rating: Gold Certification

Surface: 48, 000 m²

Lab surface: 700 m²

Capabilities:

• Total reactor capacity: 92 m³
• Reaction vessels: 1 to 6 300 L; temperature  -80°C to +250 °C
• Multi-purpose state of the art cGMP facilty: 4 independent, vertical integrated production trains 800 L train, 2 x 3 000 L trains plus 1 x 3 000 L low temperature hydrogenation reactor and 6 000 L train
• Classic two-floor layout Facility: 20 vessels with capacity between 800 and 6 000 L (glaslined and SS)
• Autoclaves (operational range up to 100 bar)
• Kilo-Lab: 3 reactors: 25 / 100 / 250 L

Flagship technologies:

• Hydrogenation
• Reductive amination
• Organometallic reactions
• Protected AADs (Aminoacid derivatives)
• Carbonylation & Hydroformylation
• Pressure aminolysis, other reactions under pressure
• Cryogenic chemistry
• Enantiopure synthesis
• Cyanation high volumes (NaCN) C-C coupling
• Reductions
• Halogenation

Last inspections:

• FDA 2018
• German Pharma Authority 2018

Certifications:

• GMP
• ISO 9001
• ISO 50001

Number of scientists: 25

EcoVadis CSR Rating: Gold Certification

Capabilities: 

• 70 m³ of GMP reactors
• 100 L – 8 000 L vessels

Flagship technologies: 

• Optical resolution
• Enzymatic hydrolysis
• Enantioselective reduction
• Low-temperature reactions (-80 °C)
• Specific reduction
• Hydrogenation (40 bar)
• Organomagnesium compounds
• Thin-layer distillation

EcoVadis CSR Rating: Gold Certification

Surface: 11, 678 m²

Lab surface: 695 m²

Capabilities: 

• 4 separate modules
• 72 m³ reactor capacity-
• 250 L – 6300 L vessels

Flagship technologies:

• Biphosphonate chemistry
• Hydrogenation (20 bar)
• Chlorination
• Cyanation (NaCN) in separate installations
• Reduction with complex hydrids
• Biocatalysis
• Manufacturing of parenteral/injectable APIs
• Separate production modules and final processing facilities

Last inspections:

• FDA 2017
• PMDA 2018
• FIMEA 2018

Number of scientists: 16

EcoVadis CSR Rating: Silver Certification

Capabilities: 

• 65 m³ of reactors
• 100 L – 2 500 L vessels

EcoVadis CSR Rating: Gold Certification

Surface: 24, 000 m²

Lab surface: 100 m²

Capabilities: 3.5 KT ASA

Flagship technologies: 

• Continuous Acetylsalicylic
• Acid Production Recycled
• Salicyclic Acid (Industrial-grade)

Last inspections: 

• USFDA, March 2018
• TFDA, May 2018

Certifications: 

• ISO 9001
• ISO 14001
• OHSAS 18001
• EcoVadis CSR Rating: Gold Certification 

Number of scientists: 11

Capabilities:

• 20 kt Salicylic ACid
• 6 kt Methyl Salicilate

Last inspections:

• ANSM, February 2018
• FDA, June 2016
• ISO, March 2018

Certifications:

• cGMP
• ISO 9001
• ISO 14001
• OHSAS 18001
• ISO 22000
• Kascher
• Halal
• EcoVadis CSR Rating: Platinium certification

Capabilities: 6 KT of Acetylsalicylic Acid

Certifications:

• cGMP
• ISO 9001
• ISO 14001
• OHSAS 18001

EcoVadis CSR Rating: Platinum Certification

Surface: 38, 619 m²

Lab surface: 560 m²

Capabilities:

• 8 KT of Paracetamol
• 4.5 KT of DC range

Flagship technologies: 

• Acetylation reaction
• Refining, granulation

Last inspections: 

• ANSM, January 2018
• NMPA ,August 2018

Certifications: 

• EU GMP
• ISO 140001
• OHSAS 18001
• EcoVadis CSR Rating: Silver Certification

Surface: 50 000 m²

Lab surface: 750 m²

Capabilities: 35 KT PAP

Flagship technologies: Catalytical hydrogenation

Last inspection: June 2017

Certifications: 

• ISO 9001
• ISO 14001
• OHSAS 18001
• Certificate of GMP issued by Norwegian Medicines Agency for PAP workshop 2 only

Capabilities: 5, 050 L of reactors (100 L to 2, 000 )

Flagship technologies: Blood fractionation for In Vitro Diagnostic

Certifications:

• ISO 9001
• ISO 14001

Number of scientists: 2

Surface : 160 000 m²

Capabilities: 

• 185 kT Phenol
• 70 kT Isopropanol
• 27 kT Acétate Isopropyle
• 5 kT DIPE

Certifications: 

• ISO 9001
• ISO 14001
• ISO 50001
• OSHAS 18001

EcoVadis CSR Rating Platinum medal