Polymers
Seqens strongly believes in the potential of new cutting-edge technologies to improve the use and efficiency of existing APIs. To support its customers, Seqens offers a range of drug delivery polymers.
The R&D centers at Seqens provide extensive knowledge and expertise in tailor-made polymers designed to meet its customers’ needs. Among our portfolio of polymers:
- Bioabsorbable and biocompatible PLA and PLGA polymers used as functional excipients for controlled and slow release (weeks to months) with a single injection of the drug product. We can provide our customers with small or bulk quantities for screening of PLA/PLGA ± PEG polymers (up to 50 references available) to improve formulation at early stages of development. These polymers are manufactured according to cGMP standards.
- VITAMIN E TPGS, a water-soluble derivative of natural Vitamin E, widely used as an excipient in pharmaceutical drug delivery innovations.
- PEKK polymers (polyetherketoneketone) useful for long-term implantable human devices with nearly unlimited life cycles (several years). These polymers are widely used in orthopedics, as well as neurological, dental, spinal and cardiovascular implants but also in PEKK-based 3D-printed bones. Catalog on demande
Seqens can also our develop other cGMP medical grade polymers such as hydroxybutyrate, (poly)ester, acrylate and methacrylate copolymers for our customers.
Main polymers products
Our locations
Nîmes Protéus by Seqens
France30000 Nîmes
Surface: 1, 000 m²
Lab surface: 500 m²
Capacities:
- 1 kilo-lab in fermentation (80 L total capacity)
- Robotic platform for highthroughput screening (HTS)
- Analytical platform for chromatography (GC, GC-MS, U-HPLC)
Flagship technologies:
- Protein engineering
- Microbiology aerobic & anaerobic
- Syngas fermentation
- Enzymes & strains fermentation
- Biochemistry
- Biocatalysis
- Design of experiments (DoE)
- Data mining
Number of scientists: 19
EcoVadis CSR Rating: Silver Certification
Porcheville
France78440 Porcheville
Surface: 40, 000 m²
Lab surface: 2, 000 m²
Capabilities:
- 4 kilo-labs
- 2 cGMP pilot plants with 11 multipurpose reactors from 100 L to 2, 800 L (total capacity of 12 m³)
- Temperature range: -15/+150°C (hastelloy reactor: -80/+200°C)
- 3 finishing rooms (agitated filter dryers, filters, dryers, milling and sieving equipments)
Flagship technologies:
- Crystallization expertise and technologiesd(salt, co-crystal and polymorph screenings, process development)
- Process Safety expertise and tecnologies
- Flow chemistry for fine chemicals
- Potent API process development
- Genotoxic Impurities
- Issue Management
- Generic A.P.I Solid state expertise
Last inspection: ANSM October 2018
Certification: GMP
Number of scientists: 110
Other: Ecosystem Pharma with integrated services
Devens
United StatesMA 01434 Devens
Lab surface: 1, 000 m²
Capabilities:
- Controlled substances (Schedule II-V)
- 5 Kilo-Labs
Number of scientists: 30
