Seqens strongly believes in the potential of new cutting-edge technologies to improve the use and efficiency of existing APIs. To support its customers, Seqens offers a range of drug delivery polymers.

Our portfolio of polymers

The R&D centers at Seqens provide extensive knowledge and expertise in tailor-made polymers designed to meet its customers’ needs. Among our portfolio of polymers:

  • Bioabsorbable and biocompatible PLA and PLGA polymers used as functional excipients for controlled and slow release (weeks to months) with a single injection of the drug product. We can provide our customers with small or bulk quantities for screening of PLA/PLGA ± PEG polymers (up to 50 references available) to improve formulation at early stages of development. These polymers are manufactured according to cGMP standards.
  • VITAMIN E TPGS, a water-soluble derivative of natural Vitamin E, widely used as an excipient in pharmaceutical drug delivery innovations.
  • PEKK polymers (polyetherketoneketone) useful for long-term implantable human devices with nearly unlimited life cycles (several years). These polymers are widely used in orthopedics, as well as neurological, dental, spinal and cardiovascular implants but also in PEKK-based 3D-printed bones. Catalog on demande

Seqens can also our develop other cGMP medical grade polymers such as hydroxybutyrate, (poly)ester, acrylate and methacrylate copolymers for our customers.

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Main aramon’lab (drug delivery polymers) products

Our locations

Address PCAS, 70 Allée Graham Bell
30000 Nîmes
Phone +33 4 66 70 64 64
Market Pharmaceutical, Specialty Ingredients & Cosmetics
Email seqensrdnimesinfo@seqens.com
More information

Surface: 1, 000 m²

Lab surface: 500 m²

Capacities:

  • 1 kilo-lab in fermentation (80 L total capacity)
  • Robotic platform for highthroughput screening (HTS)
  • Analytical platform for chromatography (GC, GC-MS, U-HPLC)

Flagship technologies: 

  • Protein engineering
  • Microbiology aerobic & anaerobic
  • Syngas fermentation
  • Enzymes & strains fermentation
  • Biochemistry
  • Biocatalysis
  • Design of experiments (DoE)
  • Data mining

Number of scientists: 19

EcoVadis CSR Rating: Silver Certification

 

Address PCAS, ZI de Limay 2, 8 Rue de Rouen
78440 Porcheville
Phone +33 1 34 79 57 00
Market Pharmaceutical, Specialty Ingredients & Cosmetics
Email ContactSeqensPCV@seqens.com
More information

Surface: 40, 000 m²

Lab surface: 2, 000 m²

Capabilities:

  • 4 kilo-labs
  • 2 cGMP pilot plants with 11 multipurpose reactors from 100 L to 2, 800 L (total capacity of 12 m³)
  • Temperature range: -15/+150°C  (hastelloy reactor: -80/+200°C)
  • 3 finishing rooms (agitated filter dryers, filters, dryers, milling and sieving equipments)

Flagship technologies:

  • Crystallization expertise and technologiesd(salt, co-crystal and polymorph screenings, process development)
  • Process Safety expertise and tecnologies
  • Flow chemistry for fine chemicals
  • Potent API process development
  • Genotoxic Impurities
  • Issue Management
  • Generic A.P.I Solid state expertise

Last inspection: ANSM  October 2018

Certification: GMP

Number of scientists: 110

Other: Ecosystem Pharma with integrated services

Address PCI Synthesis, 88 Jackson Road, Building 649
MA 01434 Devens
Phone (978) 772 2111
Market Pharmaceutical
Email Accueil@seqens.com
More information

Facility Highlights:

  • 10,000 sq. ft. facility with 6 laboratories that house 28 hoods.
  • 30 person staff, ¾ PhD’s
  • 5 kilo lab hoods

Equipment:

  • Glassware from ml to 100 liter jacketed glass vessels
  • 20 and 50 liter rotovaps
  • Various filtration equipment
  • Temperature ranges -78 – 240°C
  • Thin film evaporation
  • Flash chromatography
  • Prep chromatography
  • Micronization
  • High pressure par reactors
Address PCAS, Expansia, Route d'Avignon
30390 Aramon
Business Line Contract Manufacturing
Phone +33 4 66 57 01 01
Market Pharmaceutical
Email info.cdmo@seqens.com
More information

Capabilities: 

  • 100 m³ of GMP reactors
  • 50 L – 10 000 L vessels

Flagship technologies: 

  • Organometallic chemistry
  • Large-scale hydrogenation
  • Diborane chemistry
  • Ethylene oxide reactions
  • Biocatalysis platform
  • Polymer production (PLGA)
  • Enzymatic synthesis Skraup reactions

EcoVadis CSR Rating: Gold certification

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