Chemistry and Analytic

Seqens is a world leader in pharmaceutical and advanced specialties synthesis, capable of providing development and production services at all stages of the ingredient’s life cycle.

Seqens facilities operate on a global scale to serve key end-markets such as pharmaceuticals, health, cosmetics and advanced specialties (electronics, polymers, specialty lubricants). Our ambition is to provide our customers with safe, innovative, competitive and sustainable industrial solutions to turn ideas into reality and thereby create value.

Seqens deploys a wide range of expertise and state-of-the-art equipment to secure the process scale-up, from lab through pilot plant to commercial scale. Our pharmaceutical division provides full CMC (Chemistry, Manufacturing and Controls) services, from the initial clinical stages to the generic stage, to ensure right-on-time product delivery.

Our core expertise includes:

• Best-in-class analytical tools (HPLC-SQMS, HPLC-TQMS, HPLC-QTOF, GC-MS, GC-MSMS, , NMR, and more) for analytical method development, optimization and validation
• Best-in-class analytical tools (XRPD, DSC, TGA, DVS, MEB, DLS, PSD, BET) for solid state characterization         
• process development and production of intermediates, APIs, complex molecules and controlled substances
• alternative route design, notably through biocatalysis
• purification processes (up to 50 plates distillation) and solvent recovery
• solid-state process optimization
• design of experiments (DOE), quality by design (QbD)
• best-in-class tools for process safety assessment
• pharmacopeia (US, EUR, JP, BP, etc.) testing of raw materials
• Clinical batch release
• Stability Study according ICH
• regulatory management