Boston’Lab (R&D center for Early phase projects)

Boston’Lab (Devens) has deep experience in helping our clients in their early phase project. Boston’Lab supports you from the discovery phase of product development to the scale up of New Chemical Entities for clinical supply thanks to a team of over 30 R&D professionals (more than half are PhDs), all with deep experience in small molecule development.

Facility Highlights

• 10,000 sq. ft. facility with 6 laboratories that house 28 hoods.
• 30 person staff, ¾ PhD’s
• 5 Kilo Labs

Boston’Lab capabilities

• Process Research – Custom synthesis and synthetic route evaluation from g – kg for API’s or intermediates
• Process Development – Custom synthesis from kg – metric tons.
• cGMP manufacturing of pharmaceutical actives and intermediates for clinical trials.
• 15 DMF’s filed; 8 commercial products
• Scaled up over 150 processes

Our Devens site is also fully equipped with on-site analytical equipment including:

• GC an GC Headspace Systems
• HPLC Systems Equipped with UV-VIS, DAD, CAD and RID
• Ion Chromatography
• Gel Permeation Chromatrography
• UV-VIS, FTIR
• Karl Fischer/Moisture Balance
• Titration & Wet Chemistry Analysis
• GC-FID Systems
• GCMS
• LCMS
• Access to: NMR, X-RD, DSC

Boston’Lab Equipment

• Glassware from ml to 100 liter jacketed glass vessels
• 20 and 50 liter rotovaps
• Various filtration equipment
• Temperature ranges -78 – 240°C
• Thin film evaporation
• Flash chromatography
• Prep chromatography
• Micronization
• High pressure par reactors